FluoroFinder

	Supplier	Absolute Antibody
	Catalog #:	Ab01767-1.29-pe/cy7 (View supplier product page)
	Size	100 μg
	Price
	Antigen	Dnmt1
	Clone	RAB-C310
	Host	Mouse
	Isotype	Fab Fragment
	Conjugate	PE-Cy7
	Target Species	Human
	Applications	IP-MS
	Description	Anti-DNMT1 [RAB-C310]

	Dnmt1	This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
	PE-Cy7	PE-Cyanine®7 (PE-Cy7, RPE-Cy7) is a far red-emitting tandem fluorophore that combines phycoerythrin (PE) and Cy7. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Cy7, which emits light that can be captured with a 780/60 nm bandpass filter. PE-CY7 has an excitation peak at 565 nm and an emission peak at 778 nm, and is a suitable alternative to PE-Vio®770 (Miltenyi) and cFluor BYG781 (Cytek).

	Additional Sources

Dnmt1 / PE-Cy7 / RAB-C310