IL-1 RAcP Monoclonal / PE / REA558

Citations: (2)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-108-756 (View supplier product page)
Size 30 tests in 300 µL
Price $110.00
Antigen IL-1 RAcP
Clone REA558
Host Human
Isotype IgG1
Conjugate PE
Target Species Human
Applications FC
Description Clone REA558 recognizes the human IL-1RAcP antigen. The IL-1 receptor accessory protein (IL-1RAcP) is the second subunit required to form a functional receptor complex for IL-1alpha and beta, IL-1F6, IL-1F8, IL1-F9, and IL-33 and is necessary to mediate signal transduction. IL-1RAcP is found in a variety of tissues. | Additional information: Clone REA558 displays negligible binding to Fc receptors | | | |
About IL-1 RAcP and PE
IL-1 RAcP This gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Jul 2018]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
Citations
PMID 15722231
PMID 21600927
Additional
Sources
Reviews & Ratings
PE Excitation and Emission Spectra