FluoroFinder

	Supplier	Miltenyi Biotec
	Catalog #:	130-108-752 (View supplier product page)
	Size	9 μg in 30 μl
	Price	$90.00
	Antigen	FCRL1
	Clone	REA566
	Host	Human
	Isotype	IgG1
	Conjugate	Vio Bright FITC
	Target Species	Mouse
	Applications	FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC
	Description	Clone REA566 recognizes the mouse CD307a antigen, a single-pass type I membrane protein, which is also known as Fc receptor-like protein 1 (FcRL1) or immune receptor translocation-associated protein 5 (IRTA5). One FcRL1 isoform lacks a transmembrane domain, the other isoform has transmembrane domains and cytoplasmic ITIM and ITAM-like consensus sequences implying the inhibitory or activating signaling potential. CD307a is preferentially expressed at different stages in B cell differentiation. \| Additional information: Clone REA566 displays negligible binding to Fc receptors.

	FCRL1	This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
	Vio Bright FITC	Vio®Bright FITC has an excitation peak at 496 nm and an emission peak at 522 nm. It is recommended for use in flow cytometry and fluorescence microscopy.

$90.00
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FCRL1 Monoclonal / Vio Bright FITC / REA566