IL-1 RAcP Monoclonal / Biotin / REA558

Citations: (2)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-108-690 (View supplier product page)
Size 100 Tests in 1 ml
Price $265.00
Antigen IL-1 RAcP
Clone REA558
Host Human
Isotype IgG1
Conjugate Biotin
Target Species Human
Applications FC
Description Clone REA558 recognizes the human IL-1RAcP antigen. The IL-1 receptor accessory protein (IL-1RAcP) is the second subunit required to form a functional receptor complex for IL-1α and β, IL-1F6, IL-1F8, IL1-F9, and IL-33 and is necessary to mediate signal transduction. IL-1RAcP is found in a variety of tissues. | Additional information: Clone REA558 displays negligible binding to Fc receptors | | | |
About IL-1 RAcP and Biotin
IL-1 RAcP This gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Jul 2018]
Citations
PMID 15722231
PMID 21600927
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Biotin Excitation and Emission Spectra