ROR1 / PE / M508
ROR1 / PE / M508
Product Details
Supplier | Absolute Antibody | |
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Catalog #: | Ab03863-10.0-pe (View supplier product page) | |
Size | 100 μg | |
Price | ||
Antigen | ROR1 | |
Clone | M508 | |
Host | Human | |
Isotype | IgG1 | |
Conjugate | PE | |
Target Species | Human | |
Applications | ELISA, FC, Functional | |
Description | Anti-ROR1 [M508] |
About ROR1 and PE
ROR1 | This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012] | |
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PE | Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts. |