FluoroFinder

	Supplier	Miltenyi Biotec
	Catalog #:	130-107-861 (View supplier product page)
	Size	9 μg in 30 μl
	Price	$60.00
	Antigen	CD155
	Clone	REA519
	Host	Human
	Isotype	IgG1
	Conjugate	APC
	Target Species	Mouse
	Applications	FC
	Description	Clone REA519 recognizes the mouse CD155 antigen, which is a 70 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily. CD155, also known as poliovirus receptor (PVR), belongs to a large family of Ig molecules called nectins and nectin-like proteins, which mediate cell-cell adhesion, cell migration, and serve as entry receptors for viruses. CD155 and its family member CD112 (nectin-2) are the ligands for the activating cell-surface receptor DNAM-1 on CD8+ T cells and natural killer (NK) cells. Mouse CD155 is found on a wide variety of cells of hematopoietic origin, on CD4+ CD8+ thymocytes, regulatory T cells, other activated T cells, NKT cells, and at cell junctions on the primary vascular endothelial cells. \| Additional information: Clone REA519 displays negligible binding to Fc receptors.

	CD155	The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
	APC	Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.

$60.00
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CD155 Monoclonal / APC / REA519