FluoroFinder

	Supplier	Absolute Antibody
	Catalog #:	Ab00374-2.3-pe (View supplier product page)
	Size	200 μg
	Price
	Antigen	CD357
	Clone	YGITR 860.103.5
	Host	Mouse
	Isotype	IgG2a
	Conjugate	PE
	Target Species	Mouse
	Applications	FC
	Description	Anti-GITR [YGITR 860.103.5]

	CD357	This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
	PE	Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.

	Additional Sources

CD357 / PE / YGITR 860.103.5