Fibroblast Activation Protein alpha / PE / BIBH1 (Sibrotuzumab, huF19)
Fibroblast Activation Protein alpha / PE / BIBH1 (Sibrotuzumab, huF19)
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab04184-10.3-pe (View supplier product page) | |
| Size | 100 μg | |
| Price | ||
| Antigen | Fibroblast Activation Protein alpha | |
| Clone | BIBH1 (Sibrotuzumab, huF19) | |
| Host | Human | |
| Isotype | IgG1 | |
| Conjugate | PE | |
| Target Species | Human | |
| Applications | FC, IHC, ELISA | |
| Description | Anti-FAP alpha [BIBH1 (Sibrotuzumab, huF19)] |
About Fibroblast Activation Protein alpha and PE
| Fibroblast Activation Protein alpha | The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014] | |
|---|---|---|
| PE | Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts. |
Citations
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