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	Supplier	Absolute Antibody
	Catalog #:	Ab02165-2.3-atto488 (View supplier product page)
	Size	200 μg
	Price
	Antigen	ABCC8
	Clone	N289/16
	Host	Mouse
	Isotype	IgG2a
	Conjugate	ATTO 488
	Target Species	Hamster, Mouse, Rat
	Applications	WB
	Description	Anti-SUR1 [N289/16]

	ABCC8	The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations in the ABCC8 gene and deficiencies in the encoded protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2020]
	ATTO 488	ATTO 488 is from ATTO-Tec Gmbh has an excitation peak at 501 nm and an emission peak at 523 nm.

	Additional Sources

ABCC8 / ATTO 488 / N289/16