SHANK3 / ATTO 488 / N69/46R
SHANK3 / ATTO 488 / N69/46R
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab02310-2.0-atto488 (View supplier product page) | |
| Size | 200 μg | |
| Price | ||
| Antigen | SHANK3 | |
| Clone | N69/46R | |
| Host | Mouse | |
| Isotype | IgG2a | |
| Conjugate | ATTO 488 | |
| Target Species | Human, Mouse, Rat | |
| Applications | WB | |
| Description | Anti-Shank3 [N69/46R] |
About SHANK3 and ATTO 488
| SHANK3 | This gene is a member of the Shank gene family. Shank proteins are multidomain scaffold proteins of the postsynaptic density that connect neurotransmitter receptors, ion channels, and other membrane proteins to the actin cytoskeleton and G-protein-coupled signaling pathways. Shank proteins also play a role in synapse formation and dendritic spine maturation. Mutations in this gene are a cause of autism spectrum disorder (ASD), which is characterized by impairments in social interaction and communication, and restricted behavioral patterns and interests. Mutations in this gene also cause schizophrenia type 15, and are a major causative factor in the neurological symptoms of 22q13.3 deletion syndrome, which is also known as Phelan-McDermid syndrome. Additional isoforms have been described for this gene but they have not yet been experimentally verified. [provided by RefSeq, Mar 2012] | |
|---|---|---|
| ATTO 488 | ATTO 488 is from ATTO-Tec Gmbh has an excitation peak at 501 nm and an emission peak at 523 nm. |
Citations
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