PD-1 / PerCP-Cy5.5 / RMP1-30
PD-1 / PerCP-Cy5.5 / RMP1-30
Citations:
(10)
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 109120 (View supplier product page) | |
| Size | 100 μg | |
| Price | $358.00 | |
| Antigen | PD-1 | |
| Clone | RMP1-30 | |
| Host | Rat | |
| Isotype | IgG2b κ | |
| Conjugate | PerCP-Cy5.5 | |
| Target Species | Mouse | |
| Applications | FC | |
| Description | PerCP/Cyanine5.5 anti-mouse CD279 (PD-1) |
About PD-1 and PerCP-Cy5.5
| PD-1 | Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020] | |
|---|---|---|
| PerCP-Cy5.5 | PerCP-Cyanine® 5.5 (PerCP-Cy5.5) is a red-emitting tandem fluorophore that was originally designed to make the PerCP fluorophore more stable and increase signal intensity. The donor molecule, PerCP can be excited by the 488-nm blue laser and and transfers energy to the acceptor molecule, Cy5.5, which emitts light that can be captured with a 695/40 nm bandpass filter. PerCP-Cy5.5 has an excitation peak at 482 nm and an emission peak at 695 nm. There are superior alternatives to PerCP and PerCP-Cy5.5 including RealBlue 705 (BD Biosciences), NovaFluor Blue 690 or PerCP-eFluor™ 710. |
Images
|
Con A+IL-2-stimulated C57BL/6 splenocytes (3 days) were stained with CD279 (clone RMP1-30) PerCP/Cy5.5 (filled histogram) or rat IgG2b, κ isotype control (open histogram). |
Citations
| PMID 16493037 | ||
|---|---|---|
| PMID 19380638 | ||
| Additional Sources |
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Reviews & Ratings
PerCP-Cy5.5 Excitation and Emission Spectra
$358.00
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