p53 / ATTO 488 / X77
p53 / ATTO 488 / X77
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab02776-23.0-atto488 (View supplier product page) | |
| Size | 200 μg | |
| Price | ||
| Antigen | p53 | |
| Clone | X77 | |
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | ATTO 488 | |
| Target Species | Human, Mouse, Xenopus | |
| Applications | ELISA, IP, WB, IF | |
| Description | Anti-p53 (a.a. 16-25) [X77] |
About p53 and ATTO 488
| p53 | This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] | |
|---|---|---|
| ATTO 488 | ATTO 488 is from ATTO-Tec Gmbh has an excitation peak at 501 nm and an emission peak at 523 nm. |
Citations
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