CD11b / Brilliant Violet 650 / M1/70
CD11b / Brilliant Violet 650 / M1/70
Citations:
(51)
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 101259 (View supplier product page) | |
| Size | 50 μg | |
| Price | $273.00 | |
| Antigen | CD11b | |
| Clone | M1/70 | |
| Host | Rat | |
| Isotype | IgG2b κ | |
| Conjugate | Brilliant Violet 650 | |
| Target Species | Cynomolgus macaque, Human, Mouse, Rhesus macaque | |
| Applications | FC | |
| Description | Brilliant Violet 650 anti-mouse/human CD11b |
About CD11b and Brilliant Violet 650
| CD11b | This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] | |
|---|---|---|
| Brilliant Violet 650 | Brilliant™ Violet 650 (BV650) is a red-emitting tandem fluorophore that can be excited by the 405 nm Violet laser and collected using a 660/20 bandpass filter. BV650 has an excitation peak at 405 nm and an emission peak at 645 nm. Due to its unique Stokes shift, not many dyes have identical excitation and emission spectrums, but the nearest alternatives include SuperBright 645, Qdot® 655 and eFluor™ 650NC (ThermoFisher). BV650 exhibits a medium level of brightness and is most often used in flow cytometry, specifically, it is an alternative to nanocrystals used for intracellular flow. This dye is part of the Brilliant™ Violet dye line of fluorescent polymers. Brilliant™ Violet 421 polymer is employed as the donor molecule in a series of tandem dyes with acceptor molecules emitting at various points across the visible light spectrum. The Brilliant™ Violet dyes are a superior alternative to QDot nanocrystals and similar to SuperNova dye from Beckman Coulter and StarBright dyes from Bio-Rad. |
Images
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C57BL/6 mouse bone marrow cells were stained with CD11b (clone M1/70) Brilliant Violet 650™. Data shown was gated on myeloid cell population. |
Citations
Reviews & Ratings
Brilliant Violet 650 Excitation and Emission Spectra
$273.00
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