CD8b / ATTO 488 / YTS 156.7.7
CD8b / ATTO 488 / YTS 156.7.7
Product Details
Supplier | Absolute Antibody | |
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Catalog #: | Ab00533-8.1-atto488 (View supplier product page) | |
Size | 200 μg | |
Price | ||
Antigen | CD8b | |
Clone | YTS 156.7.7 | |
Host | Rat | |
Isotype | IgG2b | |
Conjugate | ATTO 488 | |
Target Species | Mouse | |
Applications | FC, IHC | |
Description | Anti-CD8 beta [YTS 156.7.7] |
About CD8b and ATTO 488
CD8b | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010] | |
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ATTO 488 | ATTO 488 is from ATTO-Tec Gmbh has an excitation peak at 501 nm and an emission peak at 523 nm. |