CCR5 / ATTO 488 / ST6
CCR5 / ATTO 488 / ST6
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab01124-23.0-atto488 (View supplier product page) | |
| Size | 200 μg | |
| Price | ||
| Antigen | CCR5 | |
| Clone | ST6 | |
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | ATTO 488 | |
| Target Species | Human, Rhesus macaque | |
| Applications | FC, ELISA, Surface Plasmon Resonance, Depletion | |
| Description | Anti-CCR5 [ST6] |
About CCR5 and ATTO 488
| CCR5 | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. An allelic polymorphism in this gene results in both functional and non-functional alleles; the reference genome represents the functional allele. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2015] | |
|---|---|---|
| ATTO 488 | ATTO 488 is from ATTO-Tec Gmbh has an excitation peak at 501 nm and an emission peak at 523 nm. |
Citations
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