FluoroFinder

	Supplier	Absolute Antibody
	Catalog #:	Ab01711-1.29-apc/cy7 (View supplier product page)
	Size	100 μg
	Price
	Antigen	PRDM9
	Clone	RAB-C370
	Host	Mouse
	Isotype	Fab Fragment
	Conjugate	APC-Cy7
	Target Species	Human
	Applications	ELISA, IF, IP-MS, ChIP
	Description	Anti-PRDM9 [RAB-C370]

	PRDM9	The protein encoded by this gene is a zinc finger protein with histone methyltransferase activity that catalyzes histone H3 lysine 4 trimethylation (H3K4me3) during meiotic prophase. This protein contains multiple domains, including a Kruppel-associated box (KRAB) domain, an SSX repression domain (SSXRD), a PRD1-BF1 and RIZ homologous region, a subclass of SET (PR/SET) domain, and a tandem array of C2H2 zinc fingers. The zinc finger array recognizes a short sequence motif, leading to local H3K4me3, and meiotic recombination hotspot activity. The observed allelic variation alters the DNA-binding sequence specificity of the protein, resulting in distinct meiotic recombination hotspots amongst individuals and populations. Multiple alternate alleles of this gene have been described. [provided by RefSeq, Jul 2015]
	APC-Cy7	APC-Cy7 (APC-Cyanine 7) has an excitation peak at 650 nm and an emission peak at 785 nm, and is spectrally similar to APC-CF®750 (Biotium), APC-H7 (BD Biosciences), APC-eFluor™ 780 (Thermo Fisher Scientific), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend). This dye is a member of the Cyanine® dye family, a trademark of GE heathcare.

	Additional Sources

PRDM9 / APC-Cy7 / RAB-C370