IL-18 / APC-Cy7 / 125-2H
IL-18 / APC-Cy7 / 125-2H
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab00140-1.1-apc/cy7 (View supplier product page) | |
| Size | 200 μg | |
| Price | ||
| Antigen | IL-18 | |
| Clone | 125-2H | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | APC-Cy7 | |
| Target Species | Human | |
| Applications | ELISA, IF, IP | |
| Description | Anti-IL-18 [125-2H] |
About IL-18 and APC-Cy7
| IL-18 | The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2020] | |
|---|---|---|
| APC-Cy7 | APC-Cy7 (APC-Cyanine 7) has an excitation peak at 650 nm and an emission peak at 785 nm, and is spectrally similar to APC-CF®750 (Biotium), APC-H7 (BD Biosciences), APC-eFluor™ 780 (Thermo Fisher Scientific), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend). This dye is a member of the Cyanine® dye family, a trademark of GE heathcare. |
Citations
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