IL-13 / APC-Cy7 / M1295
IL-13 / APC-Cy7 / M1295
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab03210-3.0-apc/cy7 (View supplier product page) | |
| Size | 200 μg | |
| Price | ||
| Antigen | IL-13 | |
| Clone | M1295 | |
| Host | Mouse | |
| Isotype | IgG2b | |
| Conjugate | APC-Cy7 | |
| Target Species | Human | |
| Applications | ELISA, Block/Neutralize | |
| Description | Anti-IL-13 [M1295] |
About IL-13 and APC-Cy7
| IL-13 | This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| APC-Cy7 | APC-Cy7 (APC-Cyanine 7) has an excitation peak at 650 nm and an emission peak at 785 nm, and is spectrally similar to APC-CF®750 (Biotium), APC-H7 (BD Biosciences), APC-eFluor™ 780 (Thermo Fisher Scientific), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend). This dye is a member of the Cyanine® dye family, a trademark of GE heathcare. |
Citations
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