CD86 / APC-Cy7 / OX-48
CD86 / APC-Cy7 / OX-48
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab00569-1.1-apc/cy7 (View supplier product page) | |
| Size | 200 μg | |
| Price | ||
| Antigen | CD86 | |
| Clone | OX-48 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | APC-Cy7 | |
| Target Species | Rat | |
| Applications | FC, IF | |
| Description | Anti-CD86 [OX-48] |
About CD86 and APC-Cy7
| CD86 | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011] | |
|---|---|---|
| APC-Cy7 | APC-Cy7 (APC-Cyanine 7) has an excitation peak at 650 nm and an emission peak at 785 nm, and is spectrally similar to APC-CF®750 (Biotium), APC-H7 (BD Biosciences), APC-eFluor™ 780 (Thermo Fisher Scientific), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend). This dye is a member of the Cyanine® dye family, a trademark of GE heathcare. |
Citations
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