CD49b / APC-Cy7 / GBR500 (Vatelizumab, TMC-2206)
CD49b / APC-Cy7 / GBR500 (Vatelizumab, TMC-2206)
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab04186-2.3-apc/cy7 (View supplier product page) | |
| Size | 100 μg | |
| Price | ||
| Antigen | CD49b | |
| Clone | GBR500 (Vatelizumab, TMC-2206) | |
| Host | Mouse | |
| Isotype | IgG2a | |
| Conjugate | APC-Cy7 | |
| Target Species | Cynomolgus macaque, Human, Rat, Rhesus macaque | |
| Applications | Block/Neutralize, ELISA, FC | |
| Description | Anti-CD49B [GBR500 (Vatelizumab, TMC-2206)] |
About CD49b and APC-Cy7
| CD49b | This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] | |
|---|---|---|
| APC-Cy7 | APC-Cy7 (APC-Cyanine 7) has an excitation peak at 650 nm and an emission peak at 785 nm, and is spectrally similar to APC-CF®750 (Biotium), APC-H7 (BD Biosciences), APC-eFluor™ 780 (Thermo Fisher Scientific), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend). This dye is a member of the Cyanine® dye family, a trademark of GE heathcare. |
Citations
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