FluoroFinder

	Supplier	Absolute Antibody
	Catalog #:	Ab04230-1.1-apc/cy7 (View supplier product page)
	Size	100 μg
	Price
	Antigen	CCR7
	Clone	6E1.2
	Host	Mouse
	Isotype	IgG1
	Conjugate	APC-Cy7
	Target Species	Human
	Applications	ELISA, Inhibition
	Description	Anti-CCR7 [6E1.2 ]

	CCR7	The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
	APC-Cy7	APC-Cy7 (APC-Cyanine 7) has an excitation peak at 650 nm and an emission peak at 785 nm, and is spectrally similar to APC-CF®750 (Biotium), APC-H7 (BD Biosciences), APC-eFluor™ 780 (Thermo Fisher Scientific), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend). This dye is a member of the Cyanine® dye family, a trademark of GE heathcare.

	Additional Sources

CCR7 / APC-Cy7 / 6E1.2