HIF-1 beta / APC-Cy7 / RAB-T28
HIF-1 beta / APC-Cy7 / RAB-T28
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab01726-10.29-apc/cy7 (View supplier product page) | |
| Size | 100 μg | |
| Price | ||
| Antigen | HIF-1 beta | |
| Clone | RAB-T28 | |
| Host | Human | |
| Isotype | Fab Fragment | |
| Conjugate | APC-Cy7 | |
| Target Species | Human | |
| Applications | FC, IP, IF | |
| Description | Anti-ARNT [RAB-T28] |
About HIF-1 beta and APC-Cy7
| HIF-1 beta | This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013] | |
|---|---|---|
| APC-Cy7 | APC-Cy7 (APC-Cyanine 7) has an excitation peak at 650 nm and an emission peak at 785 nm, and is spectrally similar to APC-CF®750 (Biotium), APC-H7 (BD Biosciences), APC-eFluor™ 780 (Thermo Fisher Scientific), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend). This dye is a member of the Cyanine® dye family, a trademark of GE heathcare. |
Citations
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