FluoroFinder

	Supplier	Absolute Antibody
	Catalog #:	Ab02310-8.1-apc (View supplier product page)
	Size	200 μg
	Price
	Antigen	SHANK3
	Clone	N69/46R
	Host	Rat
	Isotype	IgG2b
	Conjugate	APC
	Target Species	Human, Mouse, Rat
	Applications	WB
	Description	Anti-Shank3 [N69/46R]

	SHANK3	This gene is a member of the Shank gene family. Shank proteins are multidomain scaffold proteins of the postsynaptic density that connect neurotransmitter receptors, ion channels, and other membrane proteins to the actin cytoskeleton and G-protein-coupled signaling pathways. Shank proteins also play a role in synapse formation and dendritic spine maturation. Mutations in this gene are a cause of autism spectrum disorder (ASD), which is characterized by impairments in social interaction and communication, and restricted behavioral patterns and interests. Mutations in this gene also cause schizophrenia type 15, and are a major causative factor in the neurological symptoms of 22q13.3 deletion syndrome, which is also known as Phelan-McDermid syndrome. Additional isoforms have been described for this gene but they have not yet been experimentally verified. [provided by RefSeq, Mar 2012]
	APC	Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.

	Additional Sources

SHANK3 / APC / N69/46R