IL-21 R / APC / ATR-107
IL-21 R / APC / ATR-107
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab01293-2.3-apc (View supplier product page) | |
| Size | 200 μg | |
| Price | ||
| Antigen | IL-21 R | |
| Clone | ATR-107 | |
| Host | Mouse | |
| Isotype | IgG2a | |
| Conjugate | APC | |
| Target Species | Cynomolgus macaque, Human, Mouse | |
| Applications | Block/Neutralize | |
| Description | Anti-IL-21R [ATR-107] |
About IL-21 R and APC
| IL-21 R | The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010] | |
|---|---|---|
| APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
Citations
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