Complement Factor D / APC / D10/4
Complement Factor D / APC / D10/4
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab01589-10.0-apc (View supplier product page) | |
| Size | 200 μg | |
| Price | ||
| Antigen | Complement Factor D | |
| Clone | D10/4 | |
| Host | Human | |
| Isotype | IgG1 | |
| Conjugate | APC | |
| Target Species | Human | |
| Applications | WB, ELISA | |
| Description | Anti-Complement Factor D [D10/4] |
About Complement Factor D and APC
| Complement Factor D | This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. [provided by RefSeq, Nov 2015] | |
|---|---|---|
| APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
Citations
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