HIF-1 beta / APC / RAB-T28
HIF-1 beta / APC / RAB-T28
Product Details
Supplier | Absolute Antibody | |
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Catalog #: | Ab01726-23.0-apc (View supplier product page) | |
Size | 200 μg | |
Price | ||
Antigen | HIF-1 beta | |
Clone | RAB-T28 | |
Host | Rabbit | |
Isotype | IgG | |
Conjugate | APC | |
Target Species | Human | |
Applications | FC, IP, IF | |
Description | Anti-ARNT [RAB-T28] |
About HIF-1 beta and APC
HIF-1 beta | This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013] | |
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APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |