FluoroFinder

	Supplier	Tonbo (OWL)
	Catalog #:	35-0039_OWL (View supplier product page)
	Size	25 Tests
	Price	$27.00
	Antigen	CD3
	Clone	HIT3a
	Host	Mouse
	Isotype	IgG2a κ
	Conjugate	FITC
	Target Species	Human
	Applications	FC
	Description	The Hit3a antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor p CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.The Hit3a antibody is a widely used phenotypic marker for human T cells. In addition, binding/cross-linking of Hit3a antibody to CD3e can induce cell activation. The antibody has also been demonstrated to be cross-reactive with Chimpanzee CD3. Please choose the appropriate format for each application.

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CD3 / FITC / HIT3a