IL-18 / Alk Phosphatase / SAIC-24B-4
IL-18 / Alk Phosphatase / SAIC-24B-4
Product Details
| Supplier | Absolute Antibody | |
|---|---|---|
| Catalog #: | Ab00316-1.1-ap (View supplier product page) | |
| Size | 200 μg | |
| Price | ||
| Antigen | IL-18 | |
| Clone | SAIC-24B-4 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | Alk Phosphatase | |
| Target Species | Human | |
| Applications | ||
| Description | Anti-IL-18 [SAIC-24B-4] |
About IL-18 and Alk Phosphatase
| IL-18 | The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2020] |
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Citations
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