RNF8 / Unconjugated /
RNF8 / Unconjugated /
Product Details
Supplier | LifeSpan | |
---|---|---|
Catalog #: | LS-C749096-20 (View supplier product page) | |
Size | 20 µl | |
Price | $263.00 | |
Antigen | RNF8 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | Unconjugated | |
Target Species | Human | |
Applications | IF, WB | |
Description | RNF8 Antibody |
About RNF8 and Purified
RNF8 | The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012] |
---|