PD-1 / APC-R700 / J43

Citations: (6)
Product Details
Supplier BD Biosciences
Catalog #: 565815 (View supplier product page)
Size 50 μg
Price $254.00
Antigen PD-1
Clone J43
Host Armenian Hamster
Isotype IgG2 κ
Conjugate APC-R700
Target Species Mouse
Applications FC
Description Ms CD279 (PD-1) APC-R700 J43 50ug
About PD-1 and APC-R700
PD-1 Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
APC-R700 APC-R700 from BD Biosciences has an excitation peak at 651 nm and an emission peak at 705 nm. It's useful in flow cytometry and is spectrally similar to APC-Cy5.5, APC-Alexa 700, APC-Alexa 680 and Seta-APC-705.
Citations
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Reviews & Ratings
APC-R700 Excitation and Emission Spectra