CD127 / APC-Cy7 / A7R34

Citations: (11)
Product Details
Supplier BioLegend
Catalog #: 135040 (View supplier product page)
Size 100 μg
Price $375.00
Antigen CD127
Clone A7R34
Host Rat
Isotype IgG2a κ
Conjugate APC-Cy7
Target Species Mouse
Applications FC
Description APC/Cyanine7 anti-mouse CD127 (IL-7Ralpha)
About CD127 and APC-Cy7
CD127 The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. [provided by RefSeq, Dec 2015]
APC-Cy7 APC-Cy7 (APC-Cyanine 7) has an excitation peak at 650 nm and an emission peak at 785 nm, and is spectrally similar to APC-CF®750 (Biotium), APC-H7 (BD Biosciences), APC-eFluor™ 780 (Thermo Fisher Scientific), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend). This dye is a member of the Cyanine® dye family, a trademark of GE heathcare.
Images
  CD127 APC-Cy7 BioLegend antibody anti target:Mouse host:Rat isotype:IgG2a κ clone:A7R34

C57BL/6 mouse splenocytes were stained with CD3 FITC and CD127 (IL-7Rα) (clone A7R34) APC/Cyanine7 (left) or Rat IgG2a, κ APC/Cyanine7 control (right).

Citations
PMID 21209281
PMID 21653324
Additional
Sources
Reviews & Ratings
APC-Cy7 Excitation and Emission Spectra