ASIP / Unconjugated /
ASIP / Unconjugated /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C677205-50 (View supplier product page) | |
| Size | 50 μg | |
| Price | $294.00 | |
| Antigen | ASIP | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | ELISA, IF, IHC, IHC-P | |
| Description | ASIP Antibody |
About ASIP and Purified
| ASIP | In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes. [provided by RefSeq, Jul 2008] |
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Citations
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