Aldehyde Dehydrogenase 3 / Unconjugated /
Aldehyde Dehydrogenase 3 / Unconjugated /
Product Details
Supplier | LifeSpan | |
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Catalog #: | LS-C334098-20 (View supplier product page) | |
Size | 20 µl | |
Price | $263.00 | |
Antigen | Aldehyde Dehydrogenase 3 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | Unconjugated | |
Target Species | Human, Mouse | |
Applications | IF, IHC, WB | |
Description | ALDH3A1 Antibody |
About Aldehyde Dehydrogenase 3 and Purified
Aldehyde Dehydrogenase 3 | Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008] |
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