ZAP70 / APC / SPM362

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-11487APC (View supplier product page)
Size 100 μl
Price $619.00
Antigen ZAP70
Clone SPM362
Host Mouse
Isotype IgG2a κ
Conjugate APC
Target Species Human
Applications IHC, IHC-P
Description ZAP70 Antibody (SPM362) [Allophycocyanin]
About ZAP70 and APC
ZAP70 This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
APC Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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APC Excitation and Emission Spectra