UCHL1 / FITC / UCHL1/8107R

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-21061F (View supplier product page)
Size 100 μl
Price $629.00
Antigen UCHL1
Clone UCHL1/8107R
Host Rabbit
Isotype IgG κ
Conjugate FITC
Target Species Human, Rat
Applications IHC-P
Description UCH-L1/PGP9.5 Antibody (UCHL1/8107R) [FITC]
About UCHL1 and FITC
UCHL1 The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.[provided by RefSeq, Sep 2009]
FITC Fluorescein isothiocyanate (FITC) has an excitation peak at 495 nm and an emission peak at 519 nm. The name FITC is a misnomer in that the isothiocyanate is a reactive form of this dye. Once FITC is conjugated to an antibody, it is simply Fluorescein conjugated. FITC is one of the most widely used dyes for fluorescent applications, therefore most instruments come standard with a 488 nm laser and FITC filter set up. FITC is commonly conjugated to secondary antibodies and used in applications such as flow cytometry, immunocytochemistry, and immunohistochemistry. FITC is relatively dim, sensitive to photobleaching and it is susceptible to changes is pH. There are better performing alternatives to FITC, like Vio®Bright 515, Alexa Fluor™ 488, iFluor® 488, CF®488A and DY-488. FITC is a long-time generic dye with no sole manufacturer or trademark.
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FITC Excitation and Emission Spectra