Erythropoietin R / DyLight 550 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-19388R (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen Erythropoietin R
Clone
Host Rabbit
Isotype IgG
Conjugate DyLight 550
Target Species Human, Mouse, Rat
Applications WB, IHC-P, ICC/IF, IHC
Description EpoR (A364) detects endogenous levels of EpoR protein.
About Erythropoietin R and DyLight 550
Erythropoietin R This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
DyLight 550 DyLight™ 550 has an excitation peak at 562 nm and an emission peak at 576 nm and is spectrally similar to Alexa Fluor™ 546, Alexa Fluor™ 555, Cy3 and TRITC. DyLight™ 550 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 550 Excitation and Emission Spectra