CD11b / DyLight 680 / M1/70
CD11b / DyLight 680 / M1/70
Product Details
| Supplier | Leinco Technologies | |
|---|---|---|
| Catalog #: | C1633 (View supplier product page) | |
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| Antigen | CD11b | |
| Clone | M1/70 | |
| Host | Rat | |
| Isotype | IgG2b | |
| Conjugate | DyLight 680 | |
| Target Species | Mouse | |
| Applications | FC |
About CD11b and DyLight 680
| CD11b | This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] | |
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| DyLight 680 | DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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