ANTXR1 / DyLight 350 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-21501UV (View supplier product page)
Size 100 μl
Price $499.00
Antigen ANTXR1
Clone
Host Rabbit
Isotype IgG
Conjugate DyLight 350
Target Species Human, Mouse, Rat
Applications WB, ELISA, ICC, IF
Description TEM8/ANTXR1 Antibody [DyLight 350]
About ANTXR1 and DyLight 350
ANTXR1 This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra