ANTXR1 / Alexa Fluor 532 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-21501AF532 (View supplier product page)
Size 100 μl
Price $499.00
Antigen ANTXR1
Clone
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 532
Target Species Human, Mouse, Rat
Applications WB, ELISA, ICC, IF
Description TEM8/ANTXR1 Antibody [Alexa Fluor® 532]
About ANTXR1 and Alexa Fluor 532
ANTXR1 This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
Alexa Fluor 532 Alexa Fluor™ 532 (AF532, Alexa 532) has an excitation peak at 532 nm and an emission peak at 554 nm, and is spectrally similar to Cy®3 (GE Healthcare), TRITC, iFluor® 514 (ATT Bioquest) and iFluor® 546 (ATT Bioquest). Many flow cytometers are equipped with 532nm lasers, so while Alexa 532 can be used for flow cytometry, PE is more commonly used due to its brightness and spectral characteristics. This dye is commonly used for fluorescence microscopy applications.
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Alexa Fluor 532 Excitation and Emission Spectra