UPF1 / Alexa Fluor 750 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-370AF750 (View supplier product page)
Size 100 μl
Price $549.00
Antigen UPF1
Clone
Host Goat
Isotype IgG
Conjugate Alexa Fluor 750
Target Species Human, Mouse
Applications WB, IP
Description RENT1/UPF1/hUPF1 Antibody [Alexa Fluor® 750]
About UPF1 and Alexa Fluor 750
UPF1 This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Alexa Fluor 750 Alexa Fluor™ 750 (AF750, Alexa 750) has an excitation peak at 749 nm and an emission peak at 775 nm, and is spetrally similar to Cy®7 (GE Healthcare), APC-Fire™ 750 (BioLegend), CF®®750 (Biotium), DyLight™ 750 (ThermoFisher Scientific), iFluor® 750 (ATT Bioquest) and iFluor® 790 (ATT Bioquest). Alexa 750 is often used as a tandem fluorophore in flow cytometry or used on its own in fluorescence microscopy, in-vivo fluorescence microscopy or super-resolution microscopy applications.
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Alexa Fluor 750 Excitation and Emission Spectra