RB1 / PE / RB1/2313R

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-08940PE (View supplier product page)
Size 100 μl
Price $629.00
Antigen RB1
Clone RB1/2313R
Host Rabbit
Isotype IgG
Conjugate PE
Target Species Human, Mouse
Applications IHC-P
Description RB1 Antibody (RB1/2313R) [PE]
About RB1 and PE
RB1 The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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PE Excitation and Emission Spectra