PRDM9 / HRP / RAB-C370
PRDM9 / HRP / RAB-C370
Product Details
Supplier | Novus Biologicals, a Bio-Techne brand | |
---|---|---|
Catalog #: | NBP3-20141H (View supplier product page) | |
Size | 100 μl | |
Price | $419.00 | |
Antigen | PRDM9 | |
Clone | RAB-C370 | |
Host | Rabbit | |
Isotype | IgG κ | |
Conjugate | HRP | |
Target Species | Human | |
Applications | FC, ELISA, ICC, IF, IP, Mass Spectrometry, ChIP | |
Description | PRDM9 Antibody (RAB-C370) [HRP] - Chimeric |
About PRDM9 and HRP
PRDM9 | The protein encoded by this gene is a zinc finger protein with histone methyltransferase activity that catalyzes histone H3 lysine 4 trimethylation (H3K4me3) during meiotic prophase. This protein contains multiple domains, including a Kruppel-associated box (KRAB) domain, an SSX repression domain (SSXRD), a PRD1-BF1 and RIZ homologous region, a subclass of SET (PR/SET) domain, and a tandem array of C2H2 zinc fingers. The zinc finger array recognizes a short sequence motif, leading to local H3K4me3, and meiotic recombination hotspot activity. The observed allelic variation alters the DNA-binding sequence specificity of the protein, resulting in distinct meiotic recombination hotspots amongst individuals and populations. Multiple alternate alleles of this gene have been described. [provided by RefSeq, Jul 2015] |
---|
Citations
Reviews & Ratings
HRP Excitation and Emission Spectra
$419.00
Supplier Page
Supplier Page