PKC theta / Alexa Fluor 405 / 453416

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB4368V (View supplier product page)
Size 100 μl
Price $529.00
Antigen PKC theta
Clone 453416
Host Mouse
Isotype IgG2a
Conjugate Alexa Fluor 405
Target Species Human
Applications WB, ICS, CyTOF
Description PKC theta Antibody (453416) [Alexa Fluor® 405]
About PKC theta and Alexa Fluor 405
PKC theta Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra