Peroxiredoxin 3 / Alexa Fluor 488 / AT1F8

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-12869AF488 (View supplier product page)
Size 100 μl
Price $499.00
Antigen Peroxiredoxin 3
Clone AT1F8
Host Mouse
Isotype IgG3 κ
Conjugate Alexa Fluor 488
Target Species Human
Applications WB, ELISA, ICC, IF
Description Peroxiredoxin 3 Antibody (AT1F8) [Alexa Fluor® 488]
About Peroxiredoxin 3 and Alexa Fluor 488
Peroxiredoxin 3 This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22. [provided by RefSeq, Oct 2014]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra