Perforin / PerCP / rPRF1/8058

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-24297PCP (View supplier product page)
Size 100 μl
Price $599.00
Antigen Perforin
Clone rPRF1/8058
Host Mouse
Isotype IgG1 κ
Conjugate PerCP
Target Species Human
Applications WB, IHC-P
Description Perforin Antibody (rPRF1/8058) [PerCP]
About Perforin and PerCP
Perforin This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017]
PerCP Peridinin-Chlorophyll-Protein (PerCP) is a red-emitting fluorescent protein isolated from algae that can be excited by the 488 nm blue laser and captured with a 670/30 nm bandpass filter. PerCP exhibits a large Stokes' Shift, with an excitation peak at 482 nm and an emission peak at 675 nm. PerCP is was historically used in flow cytometry, however it is highly susceptible to photobleaching and has poor stability. Alternatives like BB700, NovaFluor Blue 690 or PerCP-eFluor™ 710 are preferred. PerCP is a generic dye that has no sole manufacturer.
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PerCP Excitation and Emission Spectra