Perforin / Alexa Fluor 700 / rPRF1/8058

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-24297AF700 (View supplier product page)
Size 100 μl
Price $599.00
Antigen Perforin
Clone rPRF1/8058
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 700
Target Species Human
Applications WB, IHC-P
Description Perforin Antibody (rPRF1/8058) [Alexa Fluor® 700]
About Perforin and Alexa Fluor 700
Perforin This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017]
Alexa Fluor 700 Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.
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Alexa Fluor 700 Excitation and Emission Spectra