Perforin / Alexa Fluor 350 / rPRF1/8058

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-24297AF350 (View supplier product page)
Size 100 μl
Price $599.00
Antigen Perforin
Clone rPRF1/8058
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 350
Target Species Human
Applications WB, IHC-P
Description Perforin Antibody (rPRF1/8058) [Alexa Fluor® 350]
About Perforin and Alexa Fluor 350
Perforin This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017]
Alexa Fluor 350 Alexa Fluor™ 350 (AF350, Alexa 350) has an excitation peak at 346 nm and an emission peak at 442 nm, and is spectrally similar in size, brightness and application to AMCA, DyLight™ 350 and CF®350. Alexa 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 350 Excitation and Emission Spectra