p57Kip2 / Alexa Fluor 532 / KIP2/8572

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-20887AF532 (View supplier product page)
Size 100 μl
Price $629.00
Antigen p57Kip2
Clone KIP2/8572
Host Mouse
Isotype IgG κ
Conjugate Alexa Fluor 532
Target Species Human
Applications IHC-P
Description p57 Kip2 Antibody (KIP2/8572) [Alexa Fluor® 532]
About p57Kip2 and Alexa Fluor 532
p57Kip2 This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Alexa Fluor 532 Alexa Fluor™ 532 (AF532, Alexa 532) has an excitation peak at 532 nm and an emission peak at 554 nm, and is spectrally similar to Cy®3 (GE Healthcare), TRITC, iFluor® 514 (ATT Bioquest) and iFluor® 546 (ATT Bioquest). Many flow cytometers are equipped with 532nm lasers, so while Alexa 532 can be used for flow cytometry, PE is more commonly used due to its brightness and spectral characteristics. This dye is commonly used for fluorescence microscopy applications.
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Alexa Fluor 532 Excitation and Emission Spectra