p53 / Alexa Fluor 700 / TP53/8183R

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-24176AF700 (View supplier product page)
Size 100 μl
Price $599.00
Antigen p53
Clone TP53/8183R
Host Rabbit
Isotype IgG κ
Conjugate Alexa Fluor 700
Target Species Human
Applications IHC-P
Description p53 Antibody (TP53/8183R) [Alexa Fluor® 700]
About p53 and Alexa Fluor 700
p53 This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
Alexa Fluor 700 Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.
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Alexa Fluor 700 Excitation and Emission Spectra