p53 / DyLight 550 / rTP53/8063

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-24174R (View supplier product page)
Size 100 μl
Price $599.00
Antigen p53
Clone rTP53/8063
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 550
Target Species Human
Applications IHC-P
Description p53 Antibody (rTP53/8063) [DyLight 550]
About p53 and DyLight 550
p53 This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
DyLight 550 DyLight™ 550 has an excitation peak at 562 nm and an emission peak at 576 nm and is spectrally similar to Alexa Fluor™ 546, Alexa Fluor™ 555, Cy3 and TRITC. DyLight™ 550 is most commonly used in flow cytometery and fluorescence microscopy applications.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

DyLight 550 Excitation and Emission Spectra